Development and Application of Practical Methodology to Access Biologically Active Alkaloids Using Alkoxyamide

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Amide functional groups play a significant role in a variety of areas such as medicinal drugs and chemical fibers. Therefore, organic chemists have developed the efficient synthesis of amide bonds. On the other hand, functionalization of the generated amide carbonyl groups is less explored than their construction due to the high stability of the amide. In this study, we succeeded to functionalize the amide group using the unique properties of alkoxyamides.