Development of a hand-held chemical image scanner for the permeability mapping of a cell monolayer

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In this study, a hand-held chemical image scanner was developed. The novel scanning light source was realized by using a light spot on a small display module. The measurement system can be smaller and cheaper compared to the conventional system which is large and expensive. The novel system is capable of adjusting the spatial resolution and the measurement point flexibly. It can be applied for the permeability mapping of a cell monolayer.