Fluorescence detection of induction potential on chiral bio-macromolecule under pulsed magnetic field.

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We examined to detect the induction potential on a bio-helical structure under pulsed magnetic field by using potential susceptible fluorescence dye. A plasmid DNA, which has supercoiled structure, was coated by Ag nanoparticles to increase the conductivity, and then was bounded with fluorescein. The functionalized plasmid DNA was dispersed in a saline and the fluorescence change accompanied with the pulsed magnetic field was observed. This fluorescence change took place with ～100 μs delay from the applied magnetic field. It was suggested that this is due to the orientation caused by the interaction between the pulsed magnetic field and the induced magnetic momentum in the helical structure.