Regulatory mechanism of flagellar and ciliary movement via calcium signaling

为了解鞭毛和纤毛对外界刺激的响应和瞬间运动调节机制，本文分析了鞭毛和纤毛在精子趋化行为和运动激活以及海胆幼虫纤毛逆转运动中的钙信号调控机制。这些研究揭示了精子趋化剂的感觉机制、鞭毛不对称的钙独立调控机制、精子运动激活中的cAMP信号和纤毛逆转运动中的钙内流。

To understand how flagella and cilia respond to external stimuli and instantaneously modify their movement, regulatory mechanisms of flagellar and ciliary movement via calcium signaling during sperm chemotactic behavior and motility activation in Ciona intestinalis and ciliary reversal movement in sea urchin larvae were analyzed. Sensory mechanism of sperm chemoattractant, calcium-independent regulatory mechanism of flagellar asymmetry, cAMP signaling in sperm motility activation and calcium influx during ciliary reversal movement were revealed by these studies.