Quantitative Analysis of Morphogenesis by Whole-animal 4D-imaging

点击翻译按钮获取中文摘要

To understand morphogenesis at single-cell-level in chordate organogenesis period, ascidian embryo was used in this study. By 3D imaging of ascidian larva, a novel peripheral neuron network structure was found at larval outer tunic. Computer model of the tailbud embryo were made. By 3D-live(4D) imaging of neural tube closure, it was suggested that two independent cell movements accomplish the closure. Thus high-resolution imaging of ascidian embryogenesis enables us to understand how each cell cause morphogenesis of tissue, organ and whole-animal level.