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Investigation into differentiation effect of TGF beta for cancer stem cells in bone-metastatic prostate cancer cells

Investigation into differentiation effect of TGF beta for cancer stem cells in bone-metastatic prostate cancer cells
TGFβ对骨转移性前列腺癌细胞中癌症干细胞分化作用的研究
批准号:
21790390
负责人:
SATO Shinya
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

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中文摘要
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英文摘要
We raised the possibility of the existence of cancer stem cells in bone-metastatic prostate cancer cells. We also showed that prostate cancer cell proliferation was decreased by TGF beta1 receptor inhibitors in vivo and in vitro, and clarified the significance of TGF beta signaling regulation as a new prostate cancer therapy.
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会议论文
原発巣・骨転移巣における前立腺癌幹細胞同定の試み
尝试鉴定原发肿瘤和骨转移中的前列腺癌干细胞
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [菰原義弘, Horlad Hasita, 大西紘二, 藤原章雄, 佐藤慎哉]
通讯作者: 佐藤慎哉
Tranilast suppresses prostate cancer growth and osteoclast differentiation in vivo and in vitro
曲尼司特在体内和体外抑制前列腺癌生长和破骨细胞分化
DOI: --
发表时间: 2010
期刊: The Prostate vol 70
影响因子: --
作者: [Sato S, Takahashi S, Asamoto M, Naiki T, Naiki-Ito A, Asai K, Shirai T]
通讯作者: Shirai T
Trial to identify cancer stem cells in primary and bone metastatic prostate cancers
鉴定原发性和骨转移性前列腺癌中的癌症干细胞的试验
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [佐藤慎哉、白井智之, ら]
通讯作者:
Traniast Suppresses Prostate Cancer Growth and Osteoclast Differentiation In Vivo and In Vitro
Traniast 在体内和体外抑制前列腺癌生长和破骨细胞分化
DOI: --
发表时间: 2010
期刊: The Prostate
影响因子: --
作者: [佐藤慎哉、白井智之, ら]
通讯作者:
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