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Research to clarify the factor which effect to the value of prostate specific antigen among men undergoing health checkup.

研究阐明影响接受健康检查的男性前列腺特异性抗原值的因素。

基本信息

批准号：
21790566
负责人：
SAWADA Norie
金额：
$ 2.75万
依托单位：
National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2009
资助国家：
日本
起止时间：
2009 至 2010
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21790566/
关键词：
癌前立腺特異高原前立腺特異抗原

项目摘要

Previous studies have shown relationships between lifestyle and prostate-specific antigen (PSA), a commonly used serum marker for the detection and diagnosis of prostate cancer. To examine the association between anthropometry and intake of soy food and PSA in Japanese men, we analyzed 4722 apparently healthy Japanese men who visited our screening for cancer from February 2004 to January 2009. There was significantly inverse correlation between height, weight, BMI and PSA levels. Intake of soy food, genistein and daidzein at baseline was significantly inversely correlated with PSA among men with over 30 or more BMI.

以前的研究已经表明生活方式和前列腺特异性抗原（PSA）之间的关系，PSA是检测和诊断前列腺癌的常用血清标志物。为了研究日本男性的人体测量学与大豆食品摄入量和PSA之间的关系，我们分析了2004年2月至2009年1月期间访问我们的癌症筛查的4722名明显健康的日本男性。PSA水平与身高、体重、BMI呈负相关。在BMI大于30的男性中，大豆食品、染料木黄酮和大豆苷元的摄入量与PSA呈显著负相关。