Randomized controlled trial of calcium supplementation for the chemoprevention of lifestyle-related diseases

补钙化学预防生活方式相关疾病的随机对照试验

• 批准号: 21790574
• 负责人: OYAMA Mari
• 金额: $ 2.58万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21790574/
• 关键词: 保健栄養; 生活習慣病; 化学予防; ランダム化比較試験; カルシウム; 血圧; 予防医学; 耐糖能; 動脈硬化

The aim of this study was to reveal a possible effect of calcium supplementation on risk-factor profiles of atherosclerosis in postmenopausal women. Four-hundred fifty women were divided into the following three groups : 1) receiving 500 mg/day of calcium supplement, 2) receiving 250 mg/day of calcium supplement, and 3) placebo. Risk-factor profiles were compared among the three groups. It is suggested that a calcium supplement 250 or 500 mg/day lowers blood pressure of Japanese elderly women.

本研究的目的是揭示钙补充剂对绝经后妇女动脉粥样硬化危险因素的可能影响。450名妇女被分为以下三组：1）接受500 mg/天的钙补充剂，2）接受250 mg/天的钙补充剂，3）安慰剂。比较三组之间的风险因素概况。建议补充钙250或500毫克/天降低日本老年妇女的血压。

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