Mechanism of energy metabolism in white ad i pose tissue via hypothalamus and sympathetic nervous system
Mechanism of energy metabolism in white ad i pose tissue via hypothalamus and sympathetic nervous system
批准号:
21790898
负责人:
SHIUCHI Tetsuya
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
This study investigated effect of melanocortin receptor blockade on expression of inflammatory cytokine in white adipose tissue (WAT)。结果建议i. c. v.关于agouti-related protein acutely increases the proinflammatory cytokine expression such of TNF·in epididymal WAT通过attenuation of sympathetic nerve activity inervating the tissue and stimulation of beta-adrenergic receptor,没有组织hypertrophy and food intake中的任何变化。
英文摘要
This study investigated effect of melanocortin receptor blockade on expression of inflammatory cytokine in white adipose tissue (WAT). Results suggest that i.c.v. administration of agouti-related protein acutely increases the proinflammatory cytokine expression such as TNF・in epididymal WAT via the attenuation of sympathetic nerve activity innervating the tissue and stimulation of beta-adrenergic receptor, without any change in the tissue hypertrophy and food intake.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
視床下部オレキシンによる骨格筋糖代謝調節作用
下丘脑食欲素对骨骼肌葡萄糖代谢的调节
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Toda C, Shiuchi T, Lee S, Yamato-Esaki M, Fujino Y, Suzuki A, Okamoto S, Minokoshi Y., Shiuchi T.et al., 志内哲也, 志内哲也, 志内哲也, Tetsuya Shiuchi, Tetsuya Shiuchi, 志内哲也]
通讯作者:
志内哲也
中枢レプチン投与後の骨格筋でのグルコース取込みにおけるAMPKの関与
AMPK 参与中枢瘦素给药后骨骼肌的葡萄糖摄取
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[志内哲也, 三浦進司, 江崎治]
通讯作者:
江崎治
視床下部オレキシンによる骨格筋での糖代謝調節と動機付け摂食行動との作用連関
下丘脑食欲素调节骨骼肌葡萄糖代谢与动机性饮食行为的关系
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[藤倉純二, 内藤雅喜, 中尾一和, 志内哲也]
通讯作者:
志内哲也
オレキシンによる交感神経を介した糖代謝調節メカニズム
食欲素介导的交感神经介导的糖代谢调节机制
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Toda C, Shiuchi T, Lee S, Yamato-Esaki M, Fujino Y, Suzuki A, Okamoto S, Minokoshi Y., Shiuchi T.et al., 志内哲也, 志内哲也]
通讯作者:
志内哲也
Hypothalamic orexin stimulates feeding-associated glucose metabolism in skeletal muscle via sympathetic nervous system
下丘脑食欲素通过交感神经系统刺激骨骼肌中与进食相关的葡萄糖代谢
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Tetsuya Shiuchi, Shiki Okamoto, Chitoku Toda, Yasuhiko Minokoshi]
通讯作者:
Yasuhiko Minokoshi
共 26 条
Reinforced foundation of the hypothalamus on metabolic homeostasis by exercise training
-
批准号:18H03152
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.9万
-
财政年份:2018
-
负责人:SHIUCHI Tetsuya
-
依托单位:
Exploration of the gastrointestinal switch that induces locomotion and its system
-
批准号:18K19745
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.08万
-
财政年份:2018
-
负责人:SHIUCHI Tetsuya
-
依托单位:
Novel physiological role in secreted protein by psycho-social stress
-
批准号:16K13030
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2016
-
负责人:SHIUCHI Tetsuya
-
依托单位:
Clarification of afferent pathway in exercise-induced enahncement in central regulatory sysytem of energy metabolism
-
批准号:26560398
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2014
-
负责人:SHIUCHI Tetsuya
-
依托单位: