Fetal lung cell implantation with bronchioalveolar stem cells

在我们的胎儿肺植入中，供体当然可以存活并分化。关于供体存活的机制，胎儿肺组织的特性和各种转录因子在胚胎肺形态发生中起着重要作用。我们发现TTF-1在其中发挥了很好的作用，供体可以区分追踪正常的肺形态发生。相比之下，包括分离细支气管肺泡干细胞在内的细胞植入正在进行中。

In our fetal lung implantation, donors could certainly survive and differentiate. Concerning the mechanism of survive of donors, the characteristics of fetal lung tissue and various transcriptional factor play important roles in embryonal lung morphogenesis. We demonstrated that TTF-1 plays a good role among them and donors can differentiate tracing normal lung morphogenesis. In contrast, cell implantation including the isolation of bronchioalveolar stem cells is on going project.