Basic research of photodynamic therapy for the malignant glioma using a newly photosensitizer.
Basic research of photodynamic therapy for the malignant glioma using a newly photosensitizer.
新型光敏剂光动力治疗恶性胶质瘤的基础研究。
批准号：
21791346
负责人：
SUGAWARA Kenichi
金额：
$2.75万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2009
资助国家：
日本
项目状态：
已结题
起止时间：
2009 至 2010
中文摘要
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英文摘要
Various photosensitizers are used in a photodynamic therapy for human malignant gliomas. However, no satisfactory results are obtained because of low cytotoxicities. We experimented using a porphyrin derivative by silylation, which increased production efficiency of singlet oxygen with cytotoxicity compared with other photosensitizers. Photodynamic therapy of human malignant gliomas using this newly photosensitizer may be possible.
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