The mechanisms of cytokine-induced encephalopathy and influence on anesthesia
The mechanisms of cytokine-induced encephalopathy and influence on anesthesia
批准号:
21791461
负责人:
HAYASHI Shiho
金额:
$1.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
我进行了一项研究,以确认细胞因子水平是否会影响乙酰胆碱神经元。大鼠腹腔注射脂多糖。将微透析探头插入脑内,取标本。用高效液相色谱仪测定乙酰胆碱水平。结果表明,注射脂多糖后,大鼠脑组织细胞外乙酰胆碱水平与对照组无显著差异。
英文摘要
I conducted research to confirm if cytokine levels affect acetylcholine neuron. Lipopolysaccharide was injected to rats intraperitoneally. Microdialysis probe was inserted into brain and samples were obtained. The acetylcholine levels were measured using HPLC system. Our results showed that the extracellular acetylcholine levels of rat brain after LPS injection were not significantly different from control levels.
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