The effect of volatile anesthetics on calcium oscillation in astrocyte

谷氨酸能神经元一直是挥发性麻醉药靶点的候选者之一。已有研究表明，星形胶质细胞调节突触间隙谷氨酸的释放。这种调节与钙振荡有关。本研究的目的是阐明在使用或不使用挥发性麻醉药的情况下，钙振荡与谷氨酸释放的关系。由于谷氨酸的浓度差异很大，所以结果没有显著的相关性。

Glutamatergic neurons have been one of the candidates for the target site of volatile anesthetics. It has been shown that astrocyte regulate the release of glutamate at synaptic cleft. This regulation is associated with calcium oscillation. The purpose of this study was to elucidate the relationship between calcium oscillation and glutamate release in the condition with or without volatile anesthetics. The result was no significant association because of the concentration of glutamate was vary widely.