The effect of volatile anesthetics for the myocardial microperfusion in systolic and diastolic phase.

作为心脏肌肉的心肌不断地重复收缩和舒张。为了揭示挥发性麻醉药对心肌供血微血管的作用，我们对大鼠心肌进行切片，观察血管活性药物和挥发性麻醉药对心肌微血管直径的影响。在血管收缩药物作用下，心肌毛细血管表现出收缩，而在血管扩张药物作用下，没有观察到稳定的松弛反应。人们认为这种研究方法不合适。

The myocardium that is the muscle of the heart has repeated contraction and relaxation continuously. In order to reveal the action of the volatile anesthetic to the microvessel which supplies blood to the myocardium, we sliced the cardiac muscle of the rat and observed the myocardial microvessel how vessel diameter would change under the influence of vasoactive drugs and volatile anesthetics. Although the capillary vessels in a myocardium showed the contraction under the vasoconstrictor drug, the stable relaxation response by a vasodilator drug was not observed. It was thought that the method of study was unsuitable.