Comprehensive research on epigenetics in male infertility

基因的表达受到选择性的控制。细胞的个性是由激活的基因组合决定的，因此它使整个个体的生理功能发挥作用。表观遗传学是基因表达的调控机制之一。最近的报道表明，表观遗传控制在胚胎学或肿瘤学中很重要。在哺乳动物精子发生过程中，生精细胞通过复杂的基因表达通过减数分裂发育成功能配子。我们的研究表明，某些在精子发生中重要的基因参与了对其表达的表观遗传控制。

The gene expression is selectively controlled. The individuality of the cell is determined by combination of activated genes so that it makes the physiological functions as the entire individual. Epigenetics is taking part as one of the control mechanisms of gene expression. Recent reports showed that epigenetic control is important in embryology or oncology. In mammalian spermatogenesis, spermatogenic cells develop into functional gametes through meiosis with complex gene expression. Our study suggested that certain genes important in spermatogenesis are involved in epigenetic control of its expression.