Analysis of the cell cycle in infected culture cell of Neisseria gonorrhoeae.

在本研究中，我证实了淋球菌感染在培养细胞中引起G1期阻滞的普遍性。我通过MLST分析检查了不同菌株的G1期阻滞能力。宿主细胞使用HeLa细胞。在40个不同系统发育的菌株中，没有发现引起G1期阻滞的菌株。显著性差异轻微检查了批准的两种菌株的细胞因子产生的定量变化，但未识别出菌株之间的显著性差异。提示淋球菌感染细胞的G1期阻滞可能是由某一株淋球菌引起的，而不是一种普遍现象。

In this study, I confirmed the universality of G1 arrest caused by gonococcus infection in culture cell. I examined about the G1 arrest ability of various strains varied by MLST analysis. The host cell used HeLa cell. In the strain of 40 different phylesis, there was not the strains which significantly caused G1 arrest. Significant difference slightly examined a quantitative alteration of the cytokine production about approved two strains, but the significant difference between the strains was not recognized. These results indicated that the possibility that the G1 arrest in the gonococcus infection cell was caused by the certain strain which was not a general phenomenon.