课题基金 / 基金详情

Antitumor effect of siRNA on endometrial cancer

Antitumor effect of siRNA on endometrial cancer
siRNA对子宫内膜癌的抗肿瘤作用
批准号:
21791573
负责人:
YANOKURA Megumi
金额:
$4.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

项目摘要

项目成果

YANOKURA Megumi的其他基金

相似基金

相关文献

中文摘要
翻译
HEC-1B细胞移植裸鼠后3周发生肿瘤。当天及之后给予药物。紫杉醇+Aurora-A siRNA治疗组小鼠的肿瘤直径与其他治疗组相比显著减小(P<0. 05)。05)。paclitaxel+Aurora-A siRNA治疗后,GFP荧光信号也明显减弱,Aurora-A siRNA可能具有增加子宫内膜肿瘤对paclitaxel治疗敏感性的潜力。
英文摘要
Tumor development occurred 3 weeks after transplantation of HEC-1B cells in nude mice. Drugs were administered on that day and thereafter. The tumor diameter significantly decreased in mice treated with paclitaxel+Aurora-A siRNA compared with the results for other treatments(P<0. 05). The GFP fluorescence signal also markedly decreased after treatment with paclitaxel+Aurora-A siRNA.Aurora-A siRNA may have the potential to increase the sensitivity of endometrial tumors to treatment with paclitaxel.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Reprogramming study of endometrial cancer cells for restoring fertility
  • 批准号:
    18K09272
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.83万
  • 财政年份:
    2018
  • 负责人:
    YANOKURA Megumi
  • 依托单位:
Genome-wide DNA methylation analysis in endometrial cancer
  • 批准号:
    15K10727
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.08万
  • 财政年份:
    2015
  • 负责人:
    YANOKURA Megumi
  • 依托单位:
Combinational antitumor effect of siRNA against M phase checkpoint gene and paclitaxel on growth of human endometrial cancer
  • 批准号:
    19791163
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.36万
  • 财政年份:
    2007
  • 负责人:
    YANOKURA Megumi
  • 依托单位:
海外基金