A research and development of novel low-cytotoxic oral self-care methods for the patients who use denture adhesives.

采用纸片法检测了10种市售义齿清洁剂对白色念珠菌的抗菌活性。在这个实验中，我们检查了八种家庭护理清洁剂和两种专业清洁剂。本研究以五种家用清洁剂为研究对象，以皂洗法探讨其对乳霜型牙科黏著剂的去除效果。浸泡18 h以上，几乎所有清洗剂的去除效果都大于纯水。然而，我们在临床上使用的义齿清洁液不到12小时，因此需要进一步研究开发新的义齿清洁剂，可以更有效地去除义齿粘合剂。

We first analyzed antimicrobial activity of ten kinds of commercial denture cleaner against Candida albicans by disk method. We examined eight kinds of home-care cleaners and two kinds of professional cleaners in this experimentation. Antimicrobial activity of every home-care cleaner was effective enough for clinical usage although it was lower than that of professional cleaners.Moreover, we investigate removal activities of cream-type dental adhesives in five kinds of home care cleaners by soaping method. Removal effect in almost all of the cleaning agents was larger than purified water when soaking it for more than eighteen hours. However, we clinically use denture cleaner solution for less than twelve hours, so further studies are needed for the development of new denture cleaner which could remove denture adhesive more effectively.