Development of the Dental Ceramic Material with Ca modified TiO_2 Nano-tubes

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It is reported that the bone fracture often happened at the part in which the bone replacement material was filled. This is because not only the poor mechanical strength of bone replacement materials but also the bone regeneration ability of them is inferior compared with autogenous bone. We found that TiO_2 nanotube bonded to the cell and activated osteoblast without addition of biochemical factor in previous studies. The aim of this study was to develop the materials that promote the cell bonding , proliferation and differentiation by making Ca modified TiO_2 nanotube by hydrothermal synthesis.