Elucidation of the Mechanism of Odontblast Differentiation by Bone Morphogenetic Factor and Application to Regeneration
Elucidation of the Mechanism of Odontblast Differentiation by Bone Morphogenetic Factor and Application to Regeneration
批准号:
21792053
负责人:
MARUYA Yuriko
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
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英文摘要
Growth/Differentiation Factor-5 (GDF-5) is a member of the bone morphogenetic protein and promotes formation of bones and cartilages. It has been reported that GDF-5 gene is expressed in oral region. However, the roles of GDF-5 in the differentiation of dental pulp cells are unknown. Thus, we investigated the effect of GDF-5 on the differentiation of dental pulp stem cell.GDF-5 promoted production of molecules characteristic for odontoblastic phenotype. These findings suggested that GDF-5 promotes differentiation of dental pulp stem cell to odontblast.
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科研奖励(0)
会议论文
唇顎口蓋裂児の齲蝕罹患に関する実態調査
唇腭裂儿童龋齿发病率调查
DOI:
--
发表时间:
2010
期刊:
小児歯科学雑誌 48
影响因子:
--
作者:
[高崎千尋, 大島昇平, 岡田理恵子, 八若保孝, 松野美乃, 丸谷由里子]
通讯作者:
丸谷由里子
Clinical Evaluation of One-step Adhesive System
一步式粘合系统的临床评价
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[高崎千尋, 大島昇平, 岡田理恵子, 八若保孝, 松野美乃, 丸谷由里子, Yuriko Maruya]
通讯作者:
Yuriko Maruya
Development of the dental pulp stem cell differentiation derivative method using GDF-5
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批准号:24593078
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2012
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负责人:MARUYA Yuriko
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依托单位:
海外基金