Development of skin care in metabolic syndrome patients

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The purpose of this study was to grasp the actual condition of impaired skin in metabolic syndrome(MS), to elucidate the mechanism, to develop Scientifically-based skin care. We analyzed the skin tissue of MS model mouse. As a result, the thinning of the dermis and thickening of the subcutaneous fat and change of the collagen were observed. MS skin was potentially inflammatory condition. In addition, the high sensitivity to UV was revealed.Its mechanisms are involved in oxidative stress. Usefulness of antioxidant therapy in applied to the skin and oral administration has been found.