Development of micro tissue devices using cardiovascular cells

近年来，分析、合成等化工过程的一体化成为人们关注的焦点。对于进一步的集成，泵等外围工具也是不可或缺的。然而，机械设备通常需要电，因此，目前的技术具有集成度的限制。另一方面，心血管细胞或组织实际上是具有微米级复杂化学和机械功能的集成组件。利用这一点，将实现超高集成度的微流控器件。基于这一概念，本项目通过巧妙地将微结构和细胞/组织功能结合起来，开发了新的概念性生物微器件。

Recently, integration of chemical process such as analysis and synthesis has been focused on. For further integration, peripheral tools such as pumps is also indispensable to be integrated. However, mechanical devices usually require electricity, and thus, current technology has a limitation of integration. On the other hand, cardiovascular cells or tissue are really integrated components with sophisticated chemical and mechanical functions in micro size. By exploiting this, ultra highly integrated microfluidic devices will be realized. Based on this concept, new conceptual bio-microdevices were developed by sophistically combining microstructures and cell/tissue functions in this project.