Visualization of cellulase molecules at a solid/liquid interface using high-speed atomic force microscopy

我们已经成功地观察到“交通堵塞”的纤维素酶分子的表面纤维素使用高速原子力显微镜。这种“分子拥挤”不仅是基础科学的新发现，而且首次证明了纤维素酶分子的这种交通堵塞是降低纤维素酶水解速率的原因。本研究的结果提供了一个有用的指导，开发一个有效的系统，为纤维素生物质的利用不久的将来。

We have succeeded in observing "traffic jams" of cellulase molecules on the surface of cellulose using high-speed atomic force microscopy. This "molecular congestion" is not only a new finding as basic science, but also is the first proof that this traffic jam of cellulase molecules is responsible for reducing the rate of cellulase hydrolysis. The findings of the present study provide a useful guide to developing an efficient system for the utilization of cellulose biomass near future.