Visualization of cellulase molecules at a solid/liquid interface using high-speed atomic force microscopy

我们利用高速原子力显微镜成功地观察到纤维素酶分子在纤维素表面的“交通堵塞”。这种“分子拥塞”不仅是基础科学的新发现，而且首次证明纤维素酶分子的交通拥堵是导致纤维素酶水解速率降低的原因。本研究的结果为在不久的将来开发有效的纤维素生物质利用系统提供了有用的指导。

We have succeeded in observing "traffic jams" of cellulase molecules on the surface of cellulose using high-speed atomic force microscopy. This "molecular congestion" is not only a new finding as basic science, but also is the first proof that this traffic jam of cellulase molecules is responsible for reducing the rate of cellulase hydrolysis. The findings of the present study provide a useful guide to developing an efficient system for the utilization of cellulose biomass near future.