The assessment of cancer/testis antigens whether they express the earlystage of cancer and use the targets for the diagnosis for early cancer.

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Cancer/testis antigens (CTAs) are the proteins expressing various types of cancer but not normal tissues except for germline cells. To assesse whether CTAs is appropriate for the diagnosis of cancer in early stage, I performed the immediate alteration of CTAs in the various cells exposed a carcinogen. I found that cells were started to express CTAs with not only exposure a carcinogen but also acquiring malignancy. Therefore we know that CTAs are fit for the target for diagnosis of early cancer because of the immediately expression with exposure of a carcinogen in conjunction with acquiring malignancy