Long-term follow-up of patients with diffuse axonal injury and cognitive disorders using diffusion tensor imaging and functional near infrared spectroscopy

使用扩散张量成像和功能近红外光谱对弥漫性轴突损伤和认知障碍患者进行长期随访

• 批准号: 21700520
• 负责人: SUGIYAMA Ken
• 金额: $ 2.66万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21700520/
• 关键词: びまん性軸索損傷; 高次脳機能障害; DTI; fNIRS

Although diffuse axonal injury (DAI)usually elicits cognitive disorders, abnormal brain findings are generally undetected by conventional imaging techniques. In this study, we found abnormal findings in the brain by using diffusion tensor imaging (DTI)and functional near infrared spectroscopy (fNIRS). In evaluation one year after, cognitive disorders had improved in DAI patients. However, DTI findings were not changed. Since apparatus broke down, the evaluation by fNIRS could not be evaluated. However, since cognitive disorders had improved, the fNIRS findings were able to consider the possibility which shows change of the improvement in DAI patients.

虽然弥漫性轴索损伤（DAI）通常会诱发认知障碍，但常规成像技术通常无法发现异常的脑部表现。在这项研究中，我们发现了异常的结果，在大脑中使用扩散张量成像（DTI）和功能近红外光谱（fNIRS）。在一年后的评估中，DAI患者的认知障碍有所改善。然而，DTI结果未发生变化。由于仪器发生故障，无法评价fNIRS评价。然而，由于认知障碍已经改善，fNIRS结果能够考虑显示DAI患者改善变化的可能性。