权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Analysis of autonomic nerve by chromogranin A during locomotor respiratory coupling

嗜铬粒蛋白A对运动呼吸耦合过程中自主神经的分析

基本信息

批准号：
21700547
负责人：
KERA Takeshi
金额：
$ 1.16万
依托单位：
Nihon institute of Medical Science
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2009
资助国家：
日本
起止时间：
2009 至 2010
项目状态：
已结题

项目摘要

We studied the effect of cycle ergometer pedal ratio calculated during locomotor respiratory coupling (LRC) on ventilatory indicators and salivary chromogranin A. Twenty-five subjects participated in our study. These subjects were divided into 2 groups. One group performed pedaling at a rate of 50 rotations per minute (rpm), and the other group performed pedaling at 40 rpm. First, the subjects pedaled at anaerobic threshold(AT) under the spontaneous breathing condition for 10 min, and then performed the same exercise under LRC. The 50-rpm group showed persistent dyspnea under LRC; however, the 40-rpm group showed a significant decrease in the respiratory rate and dyspnea.Human salivary chromogranin A level was not related to coupling between pedaling and respiration. Dyspnea decreased when the breathing rate during spontaneous breathing was lesser than that during LRC, but did not decrease when the former was greater than the latter. Nonetheless, we could not clarify the benefit of LRC on ventilatory indicators and human salivary chromogranin A.

我们研究了在运动呼吸耦合（LRC）过程中计算的踏车踏板比率对解释性指标和唾液嗜铬粒蛋白A的影响。25名受试者参加了我们的研究。这些受试者被分为2组。一组以每分钟50转（rpm）的速度进行踩踏，另一组以40 rpm的速度进行踩踏。首先，受试者在自主呼吸条件下以无氧阈值（AT）蹬踏10 min，然后在LRC条件下进行相同的运动。50-rpm组在LRC下表现出持续的呼吸困难;然而，40-rpm组表现出呼吸频率和呼吸困难的显著降低。人唾液嗜铬粒蛋白A水平与踏板和呼吸之间的耦合无关。当自主呼吸时呼吸频率小于LRC时，呼吸困难减少，但当自主呼吸时呼吸频率大于LRC时，呼吸困难没有减少。尽管如此，我们无法阐明LRC对澄清指标和人唾液嗜铬粒蛋白A的益处。