Construction of Separation Systems for Biomacromolecules by Using Self-Organized Nanotube Hydrogels

新型楔形两亲体在水中自组织，在pH刺激下形成纳米管水凝胶。纳米管水凝胶具有两个独立的空间，由纳米管之间形成的三维网状结构和纳米管本身的一维空心圆柱体组成。将纳米管水凝胶作为筛子引入毛细管电泳，可以构建生物大分子分离系统。成像技术表明，内径为8 nm的纳米管的一维空心圆柱体作为DNA分离的功能空间。

Novel wedge-shaped amphiphiles self-organized in water to from nanotube hydrogels responding on pH stimulus. The nanotube hydrogel possessed two independent spaces consisting of three-dimensional meshworks formed between nanotubes and one-dimensional hollow cylinder of the nanotube itself. Introduction of the nanotube hydrogel as sieves into the capillary electrophoresis allowed to construct a separation system for biomacromolecules. Imaging technique showed that the one-dimensional hollow cylinder of the nanotube with 8 nm inner diameter acts as a functional space for the DNA separation.