CEREBRAL BLOOD FLOW REGULATION DURING EXERCISE IN TWO ROOTS OF BRAIN ARTERY

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Blood supply to the brain originates from two roots, the internal carotid arteries (ICA) and the vertebral arteries (VA). ICA provides blood to cerebral cortex forming the anterior cerebral circulation, while VA supplies blood to occipital cortex, cerebellum, and brainstem forming the posterior cerebral circulation. Although previous studies assumed that the cerebral blood flow in two roots were similar during exercise, the present study demonstrated that there are different responses between two roots indicating regional differences in the brain circulation. Further, difference in arterial CO_2 reactivity found to be a mediator for the regional difference in the brain circulation.