Analysis of the stimulating effect of tryptophan on hepatic protein synthesis and evaluation of the effectiveness and safety of tryptophan intake
Analysis of the stimulating effect of tryptophan on hepatic protein synthesis and evaluation of the effectiveness and safety of tryptophan intake
批准号:
22380071
负责人:
YOSHIZAWA Fumiaki
金额:
$11.65万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
The stimulating effect of tryptophan on hepatic protein synthesis and the effectiveness and safety of tryptophan intake were investigated in rat. Tryptophan administration seems to lead to the increase in the level of spermine, which is involved in cell growth, in the liver and thereby to stimulate hepatic protein synthesis. Furthermore, oral administration of large dose of tryptophan induces an increase in serotonergic neuronal activity in the amygdala, a brain region involved in occurrence of the mood via serotonergic system, and thus may induce unpleasant emotions.
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DOI:
--
发表时间:
2012
期刊:
影响因子:
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DOI:
--
发表时间:
2010
期刊:
影响因子:
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作者:
[Aboshi T, Shimizu N, Nakajima Y, Honda Y, Kuwahara Y, Amano H, Mori, N., Manami Honda]
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DOI:
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2011
期刊:
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DOI:
--
发表时间:
2012
期刊:
影响因子:
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作者:
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