the development of novel therapeutic arteriogenesis by nanoparticle-mediated endothelial cell selective delivery system
the development of novel therapeutic arteriogenesis by nanoparticle-mediated endothelial cell selective delivery system
批准号:
22390160
负责人:
EGASHIRA Kensuke
金额:
$11.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Currently, there is no effective medicinal therapy for severe ischemic diseases such as critical limb ischemia (CLI). We hypothesized that nanoparticle (NP)-mediated cell-selective delivery of statins to vascular endothelium would more effectively and int
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ナノ粒子DDSを用いた血管新生治療法の開発
使用纳米颗粒 DDS 开发血管生成疗法
DOI:
--
发表时间:
2013
期刊:
Bio Clinica
影响因子:
--
作者:
[Sato A, Sakamoto N, Ando K, Kaneshiro T, Uekita H, Sugimoto K, Yamaki T, Kunii H, Nakazato K, Suzuki H, Saitoh S, Sato M, Tamagawa K, Arimura T, Kimura A, Takeishi Y, 田中靖人, Shimokawa H., Yutaka Inagaki, 的場哲哉]
通讯作者:
的場哲哉
ナノテクノロジーを基盤とする動脈硬化プラーク破綻と虚血-再灌流傷害に対する新しい治療法の開発、
基于纳米技术开发动脉粥样硬化斑块破裂和缺血再灌注损伤新疗法,
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Takahashi T, Kubo H, Fujino N, Suzuki T, Ota C, Yamada M, Yamaya M, Suzuki S, Kurosawa S., 江頭健輔]
通讯作者:
江頭健輔
Impact of nanotechnology-based endothelial cell-selective delivery of pitavastatin for therapeutic angiogenesis in critical limb ischemia
基于纳米技术的内皮细胞选择性递送匹伐他汀对严重肢体缺血治疗性血管生成的影响
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[坂元紀陽, 鶴田敏博, 北村和雄, Egashira K]
通讯作者:
Egashira K
A New Therapeutic Modality for Ischemia-Reperfusion Injury: Nanoparticle-Mediated Delivery of Pitavastatin into Reperfused Myocardium Reduced Ischemia/Reperfusion Injury in Rats
缺血再灌注损伤的新治疗方式:纳米颗粒介导的匹伐他汀递送至再灌注心肌可减少大鼠缺血/再灌注损伤
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Takahashi T, Suzuki S, Kubo H, Yamaya M, Kurosawa S, Kato M., Egashira K]
通讯作者:
Egashira K
Impact of nanotechnology-based selective delivery of pitavastatin for the development of innovative treatment of ischemic cardiovascular diseases
基于纳米技术的匹伐他汀选择性递送对缺血性心血管疾病创新治疗开发的影响
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Arimura T, Kimura A, Egashira K]
通讯作者:
Egashira K
共 37 条
formulation of bioabsorbable nanoparticle-eluting stent and Mg-Ca alloy stent
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批准号:19390216
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.15万
-
财政年份:2007
-
负责人:EGASHIRA Kensuke
-
依托单位:
Anti-inflammation therapy targeting monocyte chemoattractant protein-1 as novel strategy to treat cardiovascular disease
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批准号:14207036
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$30.62万
-
财政年份:2002
-
负责人:EGASHIRA Kensuke
-
依托单位:
MOLECULAR MECHANISMS OF CARDIOVASCULAR REMODELING INDUCED BY CHRONIC INHIBITION OF NITRIC OXIDE SYNTHESIS : ROLE OF NF-_B AND MCP-1
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批准号:11470164
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.41万
-
财政年份:1999
-
负责人:EGASHIRA Kensuke
-
依托单位:
Novel anti-MCP-1 gene therapy against restenosis and atherosclerosis
-
批准号:11557056
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.64万
-
财政年份:1999
-
负责人:EGASHIRA Kensuke
-
依托单位:
molecular mechanisms of vascular remodeling induced by blockade of nitric oxide synthesis
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批准号:08457212
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.93万
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财政年份:1996
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负责人:EGASHIRA Kensuke
-
依托单位:
Treatment and prevention of microvascular disorders
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批准号:07557346
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$1.22万
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财政年份:1995
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负责人:EGASHIRA Kensuke
-
依托单位:
THE ROLE OF ATP-SENSITIVE POTASSIUM CHANNELS IN THE MECHANISMS OF METABOLIC CORONARY VASODILATION
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批准号:06670725
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.54万
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财政年份:1994
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负责人:EGASHIRA Kensuke
-
依托单位:
海外基金