Exploration of endometrial cancer-associated microRNAs by using a functional screening method and its application to medication
Exploration of endometrial cancer-associated microRNAs by using a functional screening method and its application to medication
批准号:
22390313
负责人:
AOKI Daisuke
金额:
$12.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
The aim of this study is to identify a tumor-suppressor microRNA (miRNA) silenced by aberrant DNA methylation in endometrial cancer. By investigating escalation of expression level of microRNAs after exposure of 5-Aza-CdR in endometrial cancer cells, miR-
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子宮体癌においてエピジェネティックに制御されるmiR-34bの同定とその癌抑制効果
子宫内膜癌中表观遗传调控的miR-34b的鉴定及其抑癌作用
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Inamura M, Kawabata K, Takayama K, Tashiro K, Sakurai F, Katayama K, Toyoda M, Akutsu H, Miyagawa Y, Okita H, Kiyokawa N, Umezawa A, Hayakawa T,Furue MK, Mizuguchi H., 矢野倉 恵]
通讯作者:
矢野倉 恵
Epigenetically controlled miR-34b has antitumor activity against endometrial cancer cells.
表观遗传控制的 miR-34b 对子宫内膜癌细胞具有抗肿瘤活性。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[鈴木昭久, 宮本 強, 鹿島大靖, 塩沢丹里, Hamatani T, 落谷孝広, 塩沢丹里, 近藤格, 矢野倉 恵, Kondo T, Banno K]
通讯作者:
Banno K
子宮体癌においてエピジェネティックに制御されるmiR-34bの同定とその癌抑制効果
子宫内膜癌中表观遗传调控的miR-34b的鉴定及其抑癌作用
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[鈴木昭久, 宮本 強, 鹿島大靖, 塩沢丹里, Hamatani T, 落谷孝広, 塩沢丹里, 近藤格, 矢野倉 恵]
通讯作者:
矢野倉 恵
DOI:
10.1016/c2011-0-69819-9
发表时间:
2012-07
期刊:
影响因子:
--
作者:
[C. Bell]
通讯作者:
C. Bell
Functional screening of tumor-suppressive microRNA silenced by DNA hypermethylation in endometrial cancer.
子宫内膜癌中 DNA 高甲基化沉默的肿瘤抑制 microRNA 的功能筛选。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Takatsu A,Fuseya C,Miyamoto T,Horiuchi A, Shiozawa T, Tsuruta T]
通讯作者:
Tsuruta T
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DVELOPMENT OF HUMAN MONOCLONAL ANTIBODIES WHICH SHOW INHIBITORY EFFECTS TUMOR PROGRESSION.
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批准号:19390430
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2007
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负责人:AOKI Daisuke
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依托单位:
Development of complete human monoclonal antibodies and immune complexes for use in the treatment of cancers
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批准号:16390478
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.15万
-
财政年份:2004
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负责人:AOKI Daisuke
-
依托单位:
The analysis on functions of aberrant carbohydrates in endometrial cancer cells and the mechanism of their expression
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批准号:10671570
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:1998
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负责人:AOKI Daisuke
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依托单位:
Gene alterations of glycosyltransferase during the course of malignant tranformation in uterine endometrium
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批准号:06671685
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1994
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负责人:AOKI Daisuke
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依托单位:
The localization of beta 1,4-galactosyltransferase and its significance for malignancy
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批准号:04671018
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.45万
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财政年份:1992
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负责人:AOKI Daisuke
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依托单位:
海外基金