Properties of intercellular signal transmission determined by the fine structure of synapses

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There exists a gap between cells and neurons communicate with each other by crossing signals through this gap. In this study, we estimated the amount of transmitter molecules packed within a synaptic vesicle and the speed of diffusion of these molecules in the extracellular space. Using these estimates, we evaluated the amount of transmitter that would spillover from a synapse and the effect of these transmitters on the neighboring synapses. The visual relay synapse has specific structure that promotes such intersynaptic interactions, and we found that filtering of visual information is accomplished through these interactions.