Involvement of Polycomb group genes in cell line property of human ES and iPS cells
Involvement of Polycomb group genes in cell line property of human ES and iPS cells
Polycomb 组基因对人 ES 和 iPS 细胞细胞系特性的影响
批准号：
22500425
负责人：
TOMOTSUNE Daihachiro
金额：
$2.33万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2010
资助国家：
日本
项目状态：
已结题
起止时间：
2010 至 2012
中文摘要
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英文摘要
In this study, we produced the spontaneous differentiation, and then analyzed global changes of gene expression during the spontaneous differentiation using DNA microarray. As results of the microarray analysis using four human pluripotent stem cell lines, we found that some genes were commonly up- or down-regulated during the collapse of undifferentiated state. Furthermore, we analyzed the role of polycomb group during the collapse of undifferentiated state by ChIP-seq and ChIP-QPCR.
期刊论文(0)
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科研奖励(0)
会议论文
GLOBAL ANALYSIS OF STABILITY OF UNDIFFERENTIATED STATE IN HUMAN PLURIPOTENT STEM CELLS
人类多能干细胞未分化状态稳定性的整体分析
人类多能干细胞未分化状态稳定性的整体分析
DOI：
--
发表时间：
2013
期刊：
影响因子：
--
作者：
[Daihachiro Tomotsune, Akimi Mogi, Fengming Yue, Susumu Yoshie, Shoko Masuda, Ayana Sakurai, Daiki Fujita, Mika Morisaki-Nagai, Sakiko Takizawa-Shirasawa, Tadayuki Yokoyama, Katsunori Sasaki]
通讯作者：
Katsunori Sasaki
Fluid dynamic forces created by rotary orbital suspension culture promote cardiomyogenic differentiation of human embryonic stem cells.
旋转轨道悬浮培养产生的流体动力促进人胚胎干细胞的心肌分化。
旋转轨道悬浮培养产生的流体动力促进人胚胎干细胞的心肌分化。
DOI：
10.5405/jmbe.1356
发表时间：
2013
期刊：
J. Med. Biol. Eng
影响因子：
--
作者：
[Akimi Mogi, Shunsuke Takei, Hisashi Shimizu, Haruki Miura, Daihachiro Tomotsune*, and Katsunori Sasaki]
通讯作者：
and Katsunori Sasaki
海外基金
