To elucidate effects of a low-protein diet under molecular levels, aiming at constructing the nutrition education.

点击翻译按钮获取中文摘要

Patients with diabetic nephropathy (DN) is increased remarkably, leading to the increased number of patients with dialysis as a primary cause. Diet therapy for diabetes is high-protein diet, leading to restriction of carbohydrate. Thus, the increased numbers of DN might be related to the diet therapy. We examined how dietary protein contents affect renal manifestations and glucose levels under diabetes conditions. Under the same contentof energy and fat, a diet composed of low-protein and high-carbohydrate improved more on not only the renal manifestations but also the carbohydrate metabolism, compared to a diet composed of high-protein and low-carbohydrate.