权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Effective exercise and evaluation indexes for peripheralarterialdisease patients with intermittent claudication

外周动脉疾病间歇性跛行患者的有效运动及评价指标

基本信息

批准号：
22500678
负责人：
MURASE Norio
金额：
$ 2.58万
依托单位：
Tokyo Medical University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2010
资助国家：
日本
起止时间：
2010 至 2012
项目状态：
已结题

项目摘要

The purpose of this study was to establish the evaluation index of exercise therapyfor patients with peripheral arterial disease (PAD). The exercise therapy was conducted by using a bicycle ergometer at the intensity of the anoxic threshold (AT) provided by cardiopulmonary exercise tests (CPX) for three months. After considering maximum walkingdistance (MWD) and the relations of various indexes, the relationship between the improvement ratio of MWD before and after exercise therapy and that of recovery time (T1/2)of oxygen saturation followed by CPX in gastrocnemius muscle was significantly correlated. These results suggest that improvement of the muscle oxidative capacity in the gastrocnemius muscle contributed to improvement of walking ability, and it is thought to be an effective evaluation index.

本研究旨在建立外周动脉疾病(PAD)患者运动疗法评价指标。运动治疗采用自行车测功机，强度为心肺运动试验(CPX)提供的缺氧阈值(AT)，为期3个月。在考虑了最大步行距离(MWD)及各指标之间的关系后，运动治疗前后MWD改善率与腓肠肌血氧饱和度恢复时间(T1/2)和CPX恢复时间(T1/2)的关系显著相关。这些结果表明，腓肠肌肌肉氧化能力的提高有助于步行能力的提高，被认为是一个有效的评估指标。