Novel functions of DNA repair factors: The roles of new XPD complex in the DNA damage responses
Novel functions of DNA repair factors: The roles of new XPD complex in the DNA damage responses
批准号:
22510061
负责人:
SEKI Mineaki
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
To understand the mechanisms of genetics disorders caused by compromised nucleotide excision repair system, we started to analyze the roles of novel complex containing XPD in the response to DNA damage. In the course of study, we found another complex functioning in the cytosolic iron-sulfur (Fe-S) cluster assembly pathway. This complex has central roles in the Fe-S cluster assembly in cytosol. Moreover, we also revealed the roles of each component in the complex.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
The roles of human MMS19 in cross-link repair and FeS assembly
人类 MMS19 在交联修复和 FeS 组装中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[足立淳, 鳴海良平, 佐野聖三, 久家貴寿, 白水崇, 松本雅記, 中山敬一, 茂木章, 井倉毅, 高田穣, 朝長毅, 関 峰秋, 関峰秋]
通讯作者:
関峰秋
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity.
脊椎动物 DNA 聚合酶 N 中残基的进化保守性赋予低保真度和旁路活性。
DOI:
10.1093/nar/gkq048
发表时间:
2010
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Takata,Kei-ichi, Arana,MercedesE, Seki,Mineaki, Kunkel,ThomasA, Wood,RichardD]
通讯作者:
Wood,RichardD
DOI:
10.1016/j.molcel.2010.07.029
发表时间:
2010-08-27
期刊:
MOLECULAR CELL
影响因子:
16
作者:
[Ito, Shinsuke, Tan, Li Jing, Tanaka, Kiyoji]
通讯作者:
Tanaka, Kiyoji
DOI:
10.1016/j.jmb.2010.10.041
发表时间:
2011-01-21
期刊:
Journal of molecular biology
影响因子:
5.6
作者:
[Hogg M, Seki M, Wood RD, Doublié S, Wallace SS]
通讯作者:
Wallace SS
MMS19 is a cytosolic Fe-S assembly factor required for genome integrity.
MMS19 是基因组完整性所需的胞质 Fe-S 组装因子。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Motegi A, Takata M, 田中 亀代次]
通讯作者:
田中 亀代次
共 8 条
海外基金