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Induced Signal Transduction by Interaction between Nano-sized polymer Aggregates and Plasma Membrane of Cells

Induced Signal Transduction by Interaction between Nano-sized polymer Aggregates and Plasma Membrane of Cells
纳米聚合物聚集体与细胞质膜相互作用诱导信号转导
批准号:
22510120
负责人:
NISHIKAWA Takehiro
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

项目摘要

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中文摘要
翻译
n our research project supported by Grant-in-Aid for Scientific Research (C) (22510120), we studied how the expression level and phosphorylation of endothelial nitric oxide synthase (eNOS) are influenced when nanoparticles of amphiphilic polymer are endocytosed into vascular endothelial cells. We experimentally demonstrated that cellular uptake of the synthetic nanoparticles of polysiloxane can be processed assignals and result in the enhanced cellular responses (nitric oxide release). 交付決定額
英文摘要
n our research project supported by Grant-in-Aid for Scientific Research (C) (22510120), we studied how the expression level and phosphorylation of endothelial nitric oxide synthase (eNOS) are influenced when nanoparticles of amphiphilic polymer are endocytosed into vascular endothelial cells. We experimentally demonstrated that cellular uptake of the synthetic nanoparticles of polysiloxane can be processed assignals and result in the enhanced cellular responses (nitric oxide release). 交付決定額
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