Induced Signal Transduction by Interaction between Nano-sized polymer Aggregates and Plasma Membrane of Cells
Induced Signal Transduction by Interaction between Nano-sized polymer Aggregates and Plasma Membrane of Cells
批准号:
22510120
负责人:
NISHIKAWA Takehiro
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
n our research project supported by Grant-in-Aid for Scientific Research (C) (22510120), we studied how the expression level and phosphorylation of endothelial nitric oxide synthase (eNOS) are influenced when nanoparticles of amphiphilic polymer are endocytosed into vascular endothelial cells. We experimentally demonstrated that cellular uptake of the synthetic nanoparticles of polysiloxane can be processed assignals and result in the enhanced cellular responses (nitric oxide release). 交付決定額
英文摘要
n our research project supported by Grant-in-Aid for Scientific Research (C) (22510120), we studied how the expression level and phosphorylation of endothelial nitric oxide synthase (eNOS) are influenced when nanoparticles of amphiphilic polymer are endocytosed into vascular endothelial cells. We experimentally demonstrated that cellular uptake of the synthetic nanoparticles of polysiloxane can be processed assignals and result in the enhanced cellular responses (nitric oxide release). 交付決定額
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単層膜リポソームを反応場とする遺伝子選択系の構築
以单层脂质体为反应场的基因选择系统的构建
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[西川雄大, 角南武志, 松浦友亮, 市橋伯一, 四方哲也]
通讯作者:
四方哲也
Quantitative Gene Screening System Based on Giant Unilamellar Lipsomes and Fluorescence Activated Cell Sorter
基于巨型单层脂质体和荧光激活细胞分选仪的基因定量筛选系统
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Yuji Kunisada, Hirofumi Kishi, Fajarisandi Dimas, Melanie Yadao David, Hiroshi Nakanishi, Hideaki Kasai, Takuma Asari, Shigeo Hayashi, Takehiro Nishikawa]
通讯作者:
Takehiro Nishikawa
Interfacial Researches in Fundamental and Material Sciences of Oligo- and Polysaccharides
寡糖和多糖基础和材料科学的界面研究
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Yasutomo, M ; Tsuji, T ; Mizuki, T ; Tsuji, M ; Kawasaki, H, T. Nishikawa (J. Kadokawa Ed.)]
通讯作者:
T. Nishikawa (J. Kadokawa Ed.)
リポソームを用いた遺伝子スクリーニングシステムの構築
利用脂质体构建遗传筛查系统
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[西川雄大, 角南武志, 松浦友亮, 市橋伯一, 四方哲也]
通讯作者:
四方哲也
単層膜リポソームとセルソーターを用いる遺伝子スクリーニングシステムの構築
使用单层脂质体和细胞分选仪构建遗传筛查系统
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[西川雄大, 角南武志, 松浦友亮, 市橋伯一, 四方哲也]
通讯作者:
四方哲也
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