Preparation of film materials made of biological polysaccharidesand their composite formation with apatite

采用热压法制备了糖胺聚糖与壳聚糖的聚离子复合物，建立了生物多糖水不溶性膜的制备工艺。确定了各多糖组合的最佳工艺条件。多糖的结构和分子量对所得膜的物理性能的影响进行了评价。在体液条件下，这些薄膜上的羟基磷灰石沉积实现。为了快速获得更大尺寸的膜，还研究了膜制备工艺的改进。

The preparation process to obtain water-insoluble films of biological polysaccharides was established by hot pressing of polyion complexes made of glycosaminoglycans and chitosan. The optimal condition for each polysaccharide combination was clarified. Effects of structure and molecular weight of polysaccharides on physical properties of the resulting films were evaluated. Hydroxyapatite deposition on these films under body fluid conditions was achieved. To obtain larger sizes of the films rapidly, improvement of the film preparation process was also examined.