Evolution of genetic regulatory networks through amplification and transposition of transposons

我们研究了一些转座子在非洲爪哇中长期保持转座活性的可能性，这些转座子参与了遗传调控网络的进化。我们开发了一种新的策略来寻找和分类T2-螨转座子家族，并在异种基因组中搜索T2-螨类。此外，我们还分析了这些转座子的插入位点和邻近基因的基因表达模式，发现T2-Mite亚家族的转座和扩增可能推动了非洲爪哇遗传调控网络的进化。

We studied the possibility that some transposons whose transposition activities have been retained for a long time in Xenopushave been involved in the evolution of genetic regulatory network. We developed a new strategy to find and classify the T2-MITE transposon family and searched the Xenoousgenomes for T2-MITEs. In addition, we analyzed insertion loci of such transposons and gene expression patterns of neighbor genes and found T2-MITE subfamilies whose transposition and amplification might have driven the evolution of genetic regulatory network of Xenopus.