Characterization of a novel tripartite aromatic acids transporter, and its application for the production of industrially valuable metabolites

本研究鉴定了一种新的芳香酸转运体，该转运体参与了Comamonas sp.菌株E6对对苯二甲酸酯（TPA）的摄取。TPA转运体类似于三羧酸三方转运体（TTT），由TpiA-TpiB膜组分和TPA结合的TphC组成。E6细胞对TPA的摄取完全受到质子载体的抑制，表明TPA摄取系统需要质子动力。

This study identified a novel type of aromatic acids transporter involved in terephthalate(TPA)uptake by Comamonas sp. strain E6. The TPA transporter is similar to the tripartite tricarboxylate transporter(TTT), and consists of the TpiA-TpiB membrane components and TPA-binding TphC. TPA uptake by E6 cells was completely inhibited by a protonophore, indicating that the TPA uptake system requires a proton motive force.