Selective control of plant P450 enzymes: Development of small molecules regulating plant growth and production of sweet substances

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This study has developed the three-types of selective inhibitors of cytochrome P450 enzymes involved in biosynthesis of gibberellin that promotes seed germination and stem elongation, catabolic inactivation of abscisic acid that antagonizes gibberellin-promoted seed germination and plays an essential role in adaptive stress responses, and biosynthesis of stevioside, a sweet substance of Stevia. These inhibitors are expected to be a useful tool to control plant growth and production of sweet substances.