Changes in emotional and learning behavior evoked by environmentalstress; role of microglia in the brain
Changes in emotional and learning behavior evoked by environmentalstress; role of microglia in the brain
批准号:
22590225
负责人:
KATAFUCHI Toshihiko
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
(1) Impairment of learning and memory and fatigue in rats induced by peripheral infection stresses were blocked by minocycline, which is known to suppress activation of microglia. (2) Application of Il-1β to primary culture of rat astrocytes induces expression of serotonin transporters. (3) Poly I:C-induced impairment of water maze test in rats was due to IL-6, which expressed in the hippocampus. (4) Everyday injection of LPS (i.p.) in adult mice for 7 days induced accumulation ofβamyloid protein in the hippocampus and prefrontal cortex, which was attenuated by co-application of plasmalogens.
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Plasmalogens attenuate lipopolysaccharide-induced β-amyloid accumulation in mice
缩醛磷脂可减弱脂多糖诱导的小鼠 β-淀粉样蛋白积累
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Katafuchi, T., Ifuku, M, Fujino, T., Shiro Mawatari]
通讯作者:
Shiro Mawatari
Introduction : advances in neuroimmune biology : a comprehensive way to look at biology
简介:神经免疫生物学的进展:看待生物学的综合方法
DOI:
10.3233/nib-2011-001
发表时间:
2011
期刊:
Adv.Neuroimmuns Biol.
影响因子:
--
作者:
[Berczi, I., Katafuchi, T]
通讯作者:
T
Neuroinflammation in an animal model of poly I:C-induced fatigue. Section 3: The brain in Neuroimmunomodulation
聚 I:C 引起的疲劳动物模型中的神经炎症。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Katafuchi, T., Ifuku, M. and Take, S]
通讯作者:
S
免疫学的疲労モデル動物における脳内炎症機序
免疫疲劳模型动物的脑内炎症机制
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[片渕俊彦, 井福正隆]
通讯作者:
井福正隆
Plasmalogens attenuate lipopolysaccharide-induced b-amyloid accumulation in miceSymposium session I, Cell signaling and information processing (1)
缩醛磷脂可减弱脂多糖诱导的小鼠 b-淀粉样蛋白积累研讨会第一场,细胞信号传导和信息处理 (1)
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Katafuchi, T., Ifuku, M, Fujino, T. and Shiro Mawatari]
通讯作者:
T. and Shiro Mawatari
共 20 条
Mechanisms of pain-induced emotion and its effects on learning and memory
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批准号:19603004
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2007
-
负责人:KATAFUCHI Toshihiko
-
依托单位:
Brain mechanism and conditioning of emotional behavior induced by immunological stress
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批准号:17590207
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2005
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负责人:KATAFUCHI Toshihiko
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依托单位:
Analysis of adaptation mechanisms during environmental stress through the neural-immune interaction.
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批准号:12470011
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.09万
-
财政年份:2000
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负责人:KATAFUCHI Toshihiko
-
依托单位:
Roles of brain mast cells and their related substances in the central mechanisms of stress responses
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批准号:10557008
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$7.55万
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财政年份:1998
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负责人:KATAFUCHI Toshihiko
-
依托单位:
Roles of brain cytokines in the adaptive responses to environmental stresses
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批准号:08457021
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.8万
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财政年份:1996
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负责人:KATAFUCHI Toshihiko
-
依托单位:
Roles of brain cytokines and sympathetic nervous system in neural immune interaction during environmental stress.
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批准号:05454143
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.29万
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财政年份:1993
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负责人:KATAFUCHI Toshihiko
-
依托单位:
Roles of hypothalamo-sympathetic nervous system and circumventricular organs in stress-immune interactions.
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批准号:03670079
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.28万
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财政年份:1991
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负责人:KATAFUCHI Toshihiko
-
依托单位:
Regulation of Autonomic Nervous System by the Hypothalamo-Cerebellar System
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批准号:01570066
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1989
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负责人:KATAFUCHI Toshihiko
-
依托单位:
海外基金