Establishment of the new classification "STAT constitutive activated stomach cancer".

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Through a study of the EB virus-related gastric cancer, I found the possibility that constitutive activation of STAT3 was important to EB virus-related gastric cancer carcinogenesis and progress. In addition, in STAT3, it has been proved that it was extremely important in a carcinogenic process by many studies. I aim at the establishment of "the STAT3 constitutive activated stomach cancer", which paid its attention to transcription factor STAT3. It becomes a model of clinical and pathological approach. In addition, it may become the subgroup connected directly to the treatment and prevention. The clinicopathological significance is extremely high. I report that I elucidated one characteristic molecular side of the STAT3 constitutive activated stomach cancer, in this study.