Effects of latent infection with the insect virus in mosquitoes or propagation and prevalence of the mosquito borne virus

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In this study, we investigated the effects of latent infections with insect-specific flaviviruses in wild mosquitoes on replication and propagation of mosquito-borne flaviviruses. Growth properties of the mosquito-borne flavivirus varied depending on the presence or absence of the insect-specific flavivirus. This result suggested that latent infections with insect-specific flaviviruses might affect the transmission, ecology, and epidemiology of mosquito-borne flaviviruses.