Role of neural regenerative factors on vasa vasorum angiogenesis and remodeling of injured vasculature.

点击翻译按钮获取中文摘要

We showed that relationship between vascular maturation/stabilization of microvasculature within injured arterial walls and regeneration of peri-vascular peripheral nerve, and that nerve regenerative factors induced the renervation around the neovessels and subsequently vascular maturation/stabilization of microvessels.We demonstrated for the first time that peripheral nerves fibers were already regenerated around the microvessels in patho-physiological condition to induce the vascular maturation.