Prediction of progression and efficacy of early treatment for asymptomatic pulmonary arterial hypertension

在有肺动脉高压危险且运动时右心导管置管反应阳性的患者中，平均肺动脉压在观察期内未升高到肺动脉高压水平。但药物干预组与未干预组相比，运动时的异常反应有所改善。早期药物干预对交界性肺动脉高压患者预防肺血管重构可能有效。

In the patients who have the risks of pulmonary arterial hypertension and positive response in right heart catheterization under exercise, mean pulmonary arterial pressure had not increased to the level of pulmonary hypertension during observational period. But the abnormal responses during exercise had improved in the pharmacological intervention group compared with no intervention group. Early pharmacological intervention might be effective for patients with borderline pulmonary arterial hypertension to prevent pulmonary vascular remodeling.