The analysis of pathogenesis of idiopathic chronic urticaria and its development of diagnotic methods.
The analysis of pathogenesis of idiopathic chronic urticaria and its development of diagnotic methods.
批准号:
22591231
负责人:
TERUI Tadashi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
虽然特发性慢性荨麻疹是一种无法识别的疾病,但许多人都患有此病。我们检测了抗fceri抗体,这是自身免疫性荨麻疹的抗体之一。患者与对照组在抗体数量上无差异。对该抗体的进一步研究正在进行中。荨麻疹的发病涉及多种因素,我们发现神经肽中的P物质影响在荨麻疹中起主要作用的肥大细胞。
英文摘要
Though the idiopathic chronic urticaria is one of the unidentifiable diseases, many people have this disease. We measured the anti-FceRI antibody, which is one of the antibodies of auto immune urticaria. There are no differences between the patients and controls in quantity of antibody. Further investigations about this antibody are undergone. Many factors are involved in pathogenesis of urticaria, we showed that substance P, one of the neuropeptide, affected the mast cells which played the major role in urticaria.
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金属イオンによるマスト細胞の活性化
金属离子激活肥大细胞
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[葉山惟大, 鈴木良弘, 井上寿男, 落合豊子, 照井正, 羅智靖]
通讯作者:
羅智靖
【マスト細胞の活性化をめぐって】 ヒトマスト細胞のサブセットとその性状
[关于肥大细胞活化] 人类肥大细胞亚群及其特性
DOI:
--
发表时间:
2012
期刊:
臨床免疫・アレルギー科
影响因子:
--
作者:
[Ogawa E., Owada Y., Ikawa S., Adachi Y., Egawa T., Nemoto K., Suzuki K., Hishinuma T., Kawashima H., Kondo H., Muto M., Aiba S., Okuyama R., 岡山 吉道, 岡山 吉道]
通讯作者:
岡山 吉道
アナフィラキシーショックの病態生理
过敏性休克的病理生理学
DOI:
--
发表时间:
2012
期刊:
臨床免疫・アレルギー科
影响因子:
--
作者:
[Ogawa E., Owada Y., Ikawa S., Adachi Y., Egawa T., Nemoto K., Suzuki K., Hishinuma T., Kawashima H., Kondo H., Muto M., Aiba S., Okuyama R., 岡山 吉道]
通讯作者:
岡山 吉道
Prolonged culture of mast cells withhigh-glucose medium enhances the Fc epsilon RI-mediated degranulation response and leukotriene C4 production.
用高葡萄糖培养基延长肥大细胞培养可增强 Fc epsilon RI 介导的脱粒反应和白三烯 C4 的产生。
DOI:
--
发表时间:
2010
期刊:
Int Arch Allergy Immunol.
影响因子:
--
作者:
[Kitahata Y, Terui T.]
通讯作者:
Terui T.
Okayama YActivation of human mast cells through the platelet activating factor receptor.
冈山 Y通过血小板激活因子受体激活人类肥大细胞。
DOI:
--
发表时间:
2010
期刊:
J Allergy Clin Immunol
影响因子:
--
作者:
[Kitahata Y, Terui T., Kajiwara N]
通讯作者:
Kajiwara N
共 10 条
Analyze of the role of autoreactive antibodies in chronic spontaneous urticaria
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批准号:17K10257
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2017
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负责人:TERUI Tadashi
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依托单位:
analysis of pathogenesis of chronic spontaneous urticaria and development of new diagnostic method
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批准号:25461714
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资助金额:$3.24万
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Establishment of tretments for patients with atopic dermatitis based on the immunological background
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项目类别:Grant-in-Aid for Scientific Research (C)
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财政年份:2002
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负责人:TERUI Tadashi
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Analysis of abnormal preduction of C3 by psoriatic kerafinocyte and its control by ultraviolet irradiation
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批准号:09670865
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:1997
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负责人:TERUI Tadashi
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依托单位: