Elucidation of the biological properties of triple negative breast cancer and construction of a therapeutic strategy

点击翻译按钮获取中文摘要

Triple negative breast cancer observed high histological grade, further vascular invasion, high vascularization and proliferation potential. Results of our study demonstrated that triple negative breast cancer could be further sub-classified into three different groups (low, intermediate, high) according to the Risk Score System evaluating the following five prognostic variable (pathological tumor size, pathological node status, basal-like type, Ki67 labeling index and Microvessel Density). Difference was observed in the survival rate significantly in these three groups. In conclusion, this classification is useful as a therapeutic decision-making tool for triple negativepatients.