Therapeutic aspects from theanalysis of epithelial-mesenchymal transition (EMT) in gastric cancer.

胃癌上皮间质转化（EMT）分析的治疗方面。

• 批准号: 22591469
• 负责人: WADA Norihito
• 金额: $ 2.33万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22591469/
• 关键词: 胃十二指腸外科学; 胃癌; 上皮間葉移行; リンパ節転移; HOXB9; EMT; 浸潤転移; リンパ管新生; スキルス胃癌; ＥＭＴ; MMP; TMK-1; MKN74; 転移浸潤; 臨床病理

We have conducted our research in order to investigate the possibility of therapeutic application of the concept of epithelial-mesenchymal transition (EMT) for the treatment of advanced gastric cancer. Gastric cancer tissue from the patient treated in our

我们进行了研究，以研究上皮 - 间质转变概念（EMT）在治疗晚期胃癌的可能性。在我们的患者中接受治疗的患者的胃癌组织

项目成果

Phase I study of neoadjuvant chemoradiotherapy consisting of S-1 and cisplatin for patients with resectable advanced gastric cancer (KOGC-01)

S-1联合顺铂新辅助放化疗治疗可切除晚期胃癌的I期研究（KOGC-01）

• 发表时间: 2011
• 期刊: Anticancer Res
• 影响因子: 2
• 作者: Takahashi T;Saikawa Y;Takaishi H;Takeuchi H;Wada N;Oyama T;Fukuda K;Fukada J;Kawaguchi O;Shigematsu N;Kitagawa Y.
• 通讯作者: Kitagawa Y.

Single-incision laparoscopic surgery for partial gastrectomy in patients with a gastric submucosal tumor.

单切口腹腔镜手术对胃粘膜下肿瘤患者进行部分胃切除术。

• 发表时间: 2012
• 期刊: Am Surg
• 作者: Takahashi T;Takeuchi H;Kawakubo H;Saikawa Y;Wada N;Kitagawa Y.
• 通讯作者: Kitagawa Y.

研究について

关于研究

The assessment of the procedure of the additional gastrectomy with sentinel node (SN) mapping after endoscopic submucosal dissection (ESD)

内镜粘膜下剥离术（ESD）后附加前哨淋巴结（SN）标测胃切除术的手术评估

• 发表时间: 2011
• 作者: Suzuki H;Ogawa H;Miura K;Haneda S;Watanabe K;Ohnuma S;Sasaki H;Sase T;Kimura S;Kajiwara T;Komura T;Toshima M;Matsuda Y;Shibata C;Sasaki I;Kamiya S
• 通讯作者: Kamiya S

Phase I study of preoperative chemoradiotherapy consisted of S-1 and cisplatin for patients with curable advanced gastric cancer (KOGC-01)

由S-1和顺铂组成的术前放化疗治疗可治愈晚期胃癌的I期研究（KOGC-01）

• 发表时间: 2011
• 作者: Shiozaki A;Fujiwara H;Otsuji E;et al;Takahashi T
• 通讯作者: Takahashi T