Contribution of The Pro-inflammatory Cytokines and Aquaporin 1 & 4 in the Progression
Contribution of The Pro-inflammatory Cytokines and Aquaporin 1 & 4 in the Progression
批准号:
22591622
负责人:
TACHIBANA Osamu
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
Rathke上皮中水孔蛋白1和4的表达可能促进囊肿的进展。Rathke上皮中雄激素受体的过度表达可能诱导Rathke上皮自身增殖和腺垂体炎症。因此,水通道蛋白和雄激素受体可能是治疗症状性拉氏裂性囊肿的新靶点分子。
英文摘要
Expression of water-channel aquoporin 1 and 4 in Rathke epithelium might stimulate to progression of cyst. Over-expression of androgen receptor in Rathke epithelium might induce proliferation with Rathke epithelium itself and inflammation in adenohypophysis. So aquaporin and androgen receptor might be novel target molecules totreat with symptomatic Rathke cleft cyst.
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会议论文
Surgical significance of anatomy for supra-sellar tumor in relation to arachnoid membrane and critical perforating branches on extended transsphenoidal surgery
扩大经蝶手术中鞍上肿瘤与蛛网膜和关键穿支相关的解剖学意义
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Nagane M, Nishikawa R et al., Osamu Tachibana]
通讯作者:
Osamu Tachibana
Gonadotropin-releasing Hormone Receptor and Gonadotropin-releasing Hormone Expression in Human Meningioma Cells
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批准号:17591507
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
-
财政年份:2005
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负责人:TACHIBANA Osamu
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依托单位:
Necrogenesis in human astrocytic tumors especially based on decoy receptor 3 gene amplification and expression
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批准号:12671346
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2000
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负责人:TACHIBANA Osamu
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依托单位:
Expression of death receptor and death ligand in human astrocytic brain tumors
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批准号:10671288
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:1998
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负责人:TACHIBANA Osamu
-
依托单位:
The role of Fas/Fas ligand system in human
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批准号:08671571
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1996
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负责人:TACHIBANA Osamu
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依托单位:
海外基金